Publications

Stephen Abini-Agbomson, Kristjan Gretarsson, Rochelle M. Shih, Laura Hsieh, Tracy Lou, Pablo De Ioannes, Nikita Vasilyev, Rachel Lee, Miao Wang, Matthew Simon, Jean-Paul Armache, Evgeny Nudler, Geeta Narlikar, Shixin Liu, Chao Lu, Karim-Jean Armache (2023)
Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1
Molecular Cell. 2023 August 17; doi: 10.1016/j.molcel.2023.07.020 
[Molecular Cell]

Jonathan F Thomas, Marco Igor Valencia-Sánchez, Simone Tamburri, Susan L Gloor, Samantha Rustichelli, Victoria Godínez-López,  Pablo De Ioannes, Rachel Lee, Stephen Abini-Agbomson, Kristjan Gretarsson, Jonathan M Burg, Allison R Hickman, Lu Sun, Saarang Gopinath, Hailey Taylor, Matthew J Meiners, Marcus A Cheek, William Rice, Evgeny Nudler, Chao Lu, Michael-Christopher Keogh, Diego Pasini, Karim-Jean Armache (2023)
Structural basis of histone H2A lysine 119 deubiquitination by Polycomb Repressive Deubiquitinase BAP1/ASXL1
Science Advances. 2023 August 9; doi: 10.1126/sciadv.adg9832
[Science Advances]

Terri D. Bryson*, Pablo De Ioannes*, Marco Igor Valencia-Sánchez, Jorja G. Henikoff, Paul B. Talbert, Rachel Lee, Bernard La Scola, Karim-Jean Armache^, Steven Henikoff^ (2022)
A giant virus genome is densely packaged by stable nucleosomes within virions
Molecular Cell. 2022 December 1. doi: 10.1016/j.molcel.2022.10.020. *Equal Contribution ^Correspondence
[sciencedirect]

Paul B. Talbert, Karim-Jean Armache, Steven Henikoff (2022)
Viral histones: pickpocket's prize or primordial progenitor?
Epigenetics Chromatin. 2022 May 28; 15(1):21. doi: 10.1186/s13072-022-00454-7.
[pubmed]

Marco Valencia-Sánchez*, Stephen Abini-Agbomson*, Miao Wang, Rachel Lee, Nikita Vasilyev, Jenny Zhang, Pablo De Ioannes, Bernard La Scola, Paul Talbert, Steve Henikoff, Evengy Nudler, Albert Erives & Karim-Jean Armache^ (2021)
The structure of a virus-encoded nucleosome
Nature Structural and Molecular Biology. 2021 Apr 29. doi: 10.1038/s41594-021-00585-7. *Equal Contribution ^Correspondence
[Nat Struct Mol Biol]

Daniel Grau*, Yixiao Zhang*, Chul-Hwan Lee, Marco Valencia-Sánchez, Jenny Zhang, Miao Wang, Marlene Holder, Vladimir Svetlov, Dongyan Tan, Evengy Nudler, Danny Reinberg, Thomas Walz^, Karim-Jean Armache^ (2021)
Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction
Nature Communications. 2021 Jan 29;12(1):714. doi: 10.1038/s41467-020-20775-z. *Equal Contribution ^Correspondence
[pubmed]

Marco Igor Valencia-Sánchez*, Pablo De Ioannes*, Miao Wang*, David M. Truong, Rachel Lee, Jean-Paul Armache, Jef D Boeke, Karim-Jean Armache^ (2021)
Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation
Science. 2021 Jan 22;371(6527):eacb6663. doi: 10.1126/science.abc6663. *Equal Contribution ^Correspondence
[pubmed]

Pablo De Ioannes, Victor A.Leon, Zheng Kuang, Miao Wang, Jef D.Boeke, Andreas Hochwagen & Karim-Jean Armache^ (2019)
Structure and Function of the Orc1 BAH-Nucleosome Complex
Nature Communications, Published: 01 July 2019, Nature Communications 10, Article number:2894(2019)   ^ Correspondence
[nature communications]

Valencia-Sánchez MI*, De Ioannes P*, Wang M*, Vasilyev N, Chen R, Nudler E, Armache JP, Armache KJ^ (2019)
Structural Basis of Dot1L Stimulation by Histone H2B Lysine 120 Ubiquitination
Mol Cell. 2019 Apr 8. pii: S1097-2765(19)20233-3. doi: 10.1016/j.molcel.2019.03029[Epub ahead of print]  * Equal contribution   ^ Correspondence
[pubmed]

Lee CH*, Holder M*, Grau D, Saldaña-Meyer R, Yu JR, Ganai RA, Zhang J, Wang M, LeRoy G, Dobenecker MW, Reinberg D^, Armache KJ^  (2018)
Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2
Mol Cell. 2018 May 3;70(3):435-448.e5. * Equal contribution   ^ Correspondence
[pubmed]

Armache, K. J., Garlick, J. D., Canzio, D., Narlikar, G. J., and Kingston, R. E. (2011)
Structural Basis of Silencing: Sir3 BAH Domain in Complex with a Nucleosome at 3.0 Å Resolution
Science 334, 977
[pubmed]

Kostrewa, D*., Zeller, M*. E., Armache, K. J*., Seizl, M., Leike, K., Thomm, M., and Cramer, P. (2009)
RNA Polymerase II-TFIIB Structure and Mechanism of Transcription Initiation
Nature 462, 323-330.  * Equal contribution
[pubmed]

Brueckner, F., Armache, K. J., Cheung, A., Damsma, G. E., Kettenberger, H., Lehmann, E., Sydow, J., and Cramer, P. (2009)
Structure-Function Studies of the RNA Polymerase II Elongation Complex
Acta Crystallogr D Biol Crystallogr 65, 112-120.
[pubmed]

Cramer, P., Armache, K. J., Baumli, S., Benkert, S., Brueckner, F., Buchen, C., Damsma, G. E., Dengl, S., Geiger, S. R., Jasiak, A. J., Jawhari, A., Jennebach, S., Kamenski, T., Kettenberger, H., Kuhn, C. D., Lehmann, E., Leike, K., Sydow, J. F., and Vannini, A. (2008)
Structure of Eukaryotic RNA Polymerases
Annu Rev Biophys 37, 337-352.
[pubmed]

Jasiak, A. J*., Armache, K. J*., Martens, B., Jansen, R. P., and Cramer, P. (2006)
Structural Biology of RNA Polymerase III: Subcomplex C17/25 X-Ray Structure and 11 Subunit Enzyme Model
Mol Cell 23, 71-81.  * Equal contribution
[pubmed]

Armache, K. J., Mitterweger, S., Meinhart, A., and Cramer, P. (2005)
Structures of Complete RNA Polymerase II and Its Subcomplex, Rpb4/7
J Biol Chem 280, 7131-7134.
[pubmed]

Armache, K. J., Kettenberger, H., and Cramer, P. (2005)
The Dynamic Machinery of mRNA Elongation
Curr Opin Struct Biol 15, 197-203.
[pubmed]

Kettenberger, H*., Armache, K. J*., and Cramer, P. (2004)
Complete RNA Polymerase II Elongation Complex Structure and Its Interactions with NTP and TFIIS
Mol Cell 16, 955-965. * Equal contribution
[pubmed]

Kettenberger, H., Armache, K. J., and Cramer, P. (2003)
Architecture of the RNA Polymerase II-TFIIS Complex and Implications for mRNA Cleavage
Cell 114, 347-357.
[pubmed]

Armache, K. J., Kettenberger, H., and Cramer, P. (2003)
Architecture of Initiation-Competent 12-Subunit RNA Polymerase II
Proc Natl Acad Sci U S A 100, 6964-6968.
[pubmed]